The Way of Synthesis
Evolution of Design and Methods for Natural Products
1. Auflage Juli 2007
XIV, 1018 Seiten, Hardcover
285 Abbildungen (285 Farbabbildungen)
Mehr als 'nur' ein Lehrbuch der Naturstoffsynthese! Dieser Band erkundet verschiedene Synthesestrategien und vergleicht Herangehensweisen, die unabhängig von der jeweiligen Zielverbindung auf viele Synthesewege anzuwenden sind.
Preis: 175,00 €
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This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds.
With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry.
"I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)
The History of Synthesis
Milestones in Organic Sythesis
STRATEGY AND TACTICS
Principles and Issues Impacting Synthesis (Strategy)
Principles and Issues Impacting Design (Strategy)
Principles and Issues of Methods (Tactics)
COMPARATIVE DESIGN: CLASSICS IN TERPENE SYNTHESIS
COMPARATIVE DESIGN: CLASSICS IN ALKALOID SYNTHESIS
Daphniphyllum Alkaloids, Daphnilactone A
Josephine Wiley Reed was born and raised in North Carolina, receiving her PhD under Professor David Kingston at Virginia Tech in 1988. She holds a BA in biology with chemistry minor from the Appalachian State University and a BA in English from the University of North Carolina in Greensboro. She has taught organic chemistry courses at Virginia Tech and has held the position of Senior Research Associate at Virginia Tech, University of Florida and Brock University since 1989. She has also served as the editorial assistant for the North American Editorial Office of J. Chem. Soc. Perkin Trans 1 and 2, as a member of the organizing committee for the Symposium on the Latest Trends in Organic Synthesis, and as a consultant to TDC Research, Inc, a custom synthesis company.