Fluorine in Organic Chemistry

Chambers, Richard D.

1. Auflage September 2004
424 Seiten, Hardcover
Wiley & Sons Ltd

ISBN: 978-1-4051-0787-7

John Wiley & Sons

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The introduction of carbon - fluorine bonds into organic
compounds can profoundly influence their chemical and physical
properties when compared to their non-fluorine containing
analogues, leading to a range of man-made materials with highly
desirable properties. These molecules are of interest across the
wide spectrum of industrial and academic organic chemistry, from
pharmaceuticals, through fine and specialty chemicals to polymers.
From Prozac to Teflon, many of the most important products of the
chemical and life-science industries rely on organic fluorine
chemistry for their useful properties.

In this new book the author, internationally known for his
contribution to organic fluorine chemistry, covers both the
preparative methodologies and chemical properties of partially and
highly fluorinated organic systems. Written as an authoritative
guide to the subject for organic chemists in universities and the
pharmaceutical, agrochemical, specialty organic and polymer
industries, the book will also be an important resource for
university advanced courses.

Dick Chambers is a Fellow of the Royal Society and Emeritus
Professor of Chemistry at the University of Durham, Durham, UK.

General discussion of organic fluorine chemistry; Preparation of highly fluorinated compounds; Partial or selective fluorination; The influence of fluorine of fluorocarbon groups on some reaction centres; Nucleophilic displacement of halogen from fluorocarbon systems; Elimination reactions; Polyfluoroalkanes, polyfluoroalkenes, and derivatives; Functional compounds containing oxygen, sulphur, or nitrogen and their derivatives; Polyfluoroaromatic compounds; Organometallic reagents; References; Index

"In this second, completely revised and enlarged edition, Richard
Chambers, a leading expert in the field, brings together everything
of importance to fluorine in organic synthesis. With almost 2000
references, this long-awaited revised edition is an indipensible
source of high-quality information for everyone working in the
filed of fluorine chemistry. More generally, this comprehensive
handbook will also prove of great value to all those working in
organic chemistry"

Chemistry World

"[This] monograph makes an excellent contribution to the diverse
and rich field. [Fluorine in Organic Chemistry] is skillfully
crafted to cover various synthetic and mechanistic facets by one of
the doyens of the organofluorine chemistry." Richard D.
Chambers

"Extensive tables and figures are quite informative and well
referenced to the original literature. The author is to be
commended for succinctly covering a diverse and interdisciplinary
field in a systematic approach."

G. K. Surya Prakash

Loker Hydrocarbon Research Institute and Department of Chemistry,
University of Southern California

"[An] essential addition to the library of anyone involved in
the field but also to any university library as a standard
reference."

Physical Science Education Reviews