Medicinal Natural Products
A Biosynthetic Approach
1. Auflage Februar 2009
550 Seiten, Hardcover
Praktikerbuch
Kurzbeschreibung
Medicinal Natural Products, Third Edition provides a comprehensive and balanced introduction to natural products from a biosynthetic perspective, focusing on the metabolic sequences leading to various classes of natural products. The book builds upon fundamental chemical principles and guides the reader through a wealth of diverse natural metabolites, emphasizing those used in medicine: sources, production methods, use as drugs, semi-synthetic derivatives and synthetic analogues, and modes of action are all extensively covered. Medicinal Natural Products, Third Edition is an invaluable textbook for students of pharmacy, pharmacognosy, medicinal chemistry, biochemistry, and natural products synthesis.
Medicinal Natural Products: A Biosynthetic Approach, Third Edition, provides a comprehensive and balanced introduction to natural products from a biosynthetic perspective, focussing on the metabolic sequences leading to various classes of natural products. The book builds upon fundamental chemical principles and guides the reader through a wealth of diverse natural metabolites with particular emphasis on those used in medicine.
There have been rapid advances in biosynthetic understanding over the past decade through enzymology, gene isolation and genetic engineering. Medicinal Natural Products has been extended and fully updated in this new edition to reflect and explain these developments and other advances in the field. It retains the user-friendly style and highly acclaimed features of previous editions:
* a comprehensive treatment of plant, microbial, and animal natural products in one volume
* extensive use of chemical schemes with annotated mechanistic explanations
* cross-referencing to emphasize links and similarities
* boxed topics giving further details of medicinal materials, covering sources, production methods, use as drugs, semi-synthetic derivatives and synthetic analogues, and modes of action
Medicinal Natural Products: A Biosynthetic Approach, Third Edition, is an invaluable textbook for students of pharmacy, pharmacognosy, medicinal chemistry, biochemistry and natural products chemistry.
2. Secondary Metabolism: The Building Blocks and Construction Mechanisms.
3. The Acetate Pathway: Fatty Acids and Polyketides.
4. The Shikimate Pathway: Aromatic Amino Acids and Phenylpropanoids.
5. The Mevalonate and Methylerythritol Phosphate Pathways: Terpenoids and Steroids.
6. Alkaloids.
7. Peptides, Proteins, and Other Amino Acid Derivatives.
8. Carbohydrates.
Index.
