Pediatric Solid Organ Transplantation
2. Edition January 2007
488 Pages, Hardcover
Wiley & Sons Ltd
Pediatric Solid Organ Transplantation is a comprehensive and succinct text on all aspects of pediatric solid organ transplantation. It provides a ready source of reference, to both the basic science and organ specific surgical technique and after care. This second edition has been extensively updated in light of recent developments in this rapidly advancing area.
The only textbook devoted to the field of pediatric transplantation
* A definitive reference for all those interested in improving the care and quality of life of children undergoing solid organ transplantation
* Section on immunosuppression has been expanded by four chapters to include sections on;
- mechanisms of action
- therapies for the sensitized patient
- post-transplant lymphoproliferative disorders
- organ toxicities of immunosuppressive therapy
* A new section has been added on the many topics related to quality of life that effect survivors of pediatric transplantation
* International editorial and contributor team represents a wide geographical range and contains both recognized leaders and emerging experts
Whether you are an established sub-specialist in pediatric transplantation, a transplant surgeon, or a pediatric specialist in a related area, this book will answer all your questions about care of the pediatric patient before, during, and after transplantation.
1 The Immune Response to Organ Allografts.
2 Allorecognition Pathways.
3 Costimulation.
4 The HLA System and Histocompatibility Testing for Organ
Transplantation.
5 Gene Polymorphisms and Pharmacogenomics.
6 Genomics and Proteomics as Research Tools.
7 Tolerance: A Review of its Mechanisms in the Transplant
Setting.
Section 2 Immunosuppression and its Complications.
8 Mechanisms of Action of Immunosuppressive Agents.
9 Induction and Maintenance Immunosuppression.
10 Novel Immunosuppressants.
11 Therapies for the Allosensitized Patient.
12 Infections Post-Transplantation.
13 Post-Transplant Lymphoproliferative Disorders and
Malignancy.
14 Organ Toxicities.
Section 3 Kidney Transplantation.
15 Historical Notes.
16 Recipient Characteristics.
17 Evaluation of the Candidate.
18 Donor Evaluation, Surgical Technique and Perioperative
Management.
19 Pathology of the Kidney Allograft.
20 Post-Transplant Management.
21 Outcomes and Risk Factors.
Section 4 Liver Transplantation.
22 Historical Notes.
23 Recipient Characteristics.
24 Evaluation of the Candidate.
25 Donor Evaluation, Surgical Technique and Perioperative
Management.
26 Pathology of the Liver Allograft.
27 Post-Transplant Management.
28 Outcomes and Risk Factors.
Section 5 Heart Transplantation.
29 Historical Notes.
30 Recipient Characteristics.
31 Evaluation of the Candidate.
32 Donor Evaluation, Surgical Technique and Perioperative
Management.
33 Pathology of the Cardiac Allograft.
34 Post-Transplant Management.
35 Outcomes and Risk Factors.
Section 6 Lung and Heart-Lung Transplantation.
36 Historical Notes.
37 Recipient Characteristics.
38 Evaluation of the Candidate.
39 Donor Evaluation, Surgical Technique and Perioperative
Management.
40 Pathology of the Lung Allograft.
41 Post-Transplant Management.
42 Outcomes and Risk Factors.
Section 7 Intestinal Transplantation.
43 Historical Notes.
44 Recipient Characteristics.
45 Evaluation of the Candidate.
46 Donor Evaluation, Surgical Technique and Perioperative
Management.
47 Pathology of the Intestinal Allograft.
48 Post-Transplant Management.
49 Outcomes and Risk Factors.
Section 8 Special Issues after Pediatric
Transplantation.
50 Growth and Puberty.
51 Cognitive Development.
52 Psychosocial Adaptation and Adherence .
53 Pregnancy.
54 Gynecologic Issues.
55 Transition to Adult Care.
Index
mainly because of the basic scientific and clinical information
provided rather than for its coverage of allograft
pathology." (Pediatric and Developmental Pathology)
"This remains the only text devoted to pediatric
transplant issues and accomplishes the stated goals...It serves
to fill a void in the field."
(Doody's Review Service)
"A comprehensive text written by experienced authors on all
aspects of solid organ transplantation." (Paediatric
Endocrinology Reviews)
of Paediatrics, State University of New York, USA
Dr Steve Webber, Division of Cardiology, Children's
Hospital of Pittsburgh, USA
Dr William Harman, Associate Professor of Paediatrics,
Harvard Medical School, Boston, USA