An increasing number of pharmaceuticals in human and veterinary
medicine are being developed using advanced genetic and other
methods that focus on modification of somatic and embryonic cells.
These methods, in the setting of drug manufacture, call for new
processes that go beyond the traditional unit processes of chemical
and biological production, such as batch submerged culture.

This book is the first to describe in detail these advanced
biological processes and show how they are applied to the
production of biopharmaceuticals, from product generation and
purification to fill-finish operations.

The work explains how technologies developed in the last decade
function similarly to unit operations for producing advanced
biopharmaceuticals, such as hormones, cytokines, therapeutic
enzymes, modified proteins, and transgenic products - to name a
few. From large-scale animal cell bioreactors to patient-customized
products, this volume describes the effects of new technologies on
biopharmaceutical processes and guides users on how to apply new
technologies in process development.