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John Wiley & Sons Capillary Electropheresis in Chiral Analysis Cover Electrophoretic techniques are used to separate large charged molecules such as proteins and sugars... Product #: 978-0-471-97415-4 Regular price: $411.21 $411.21 In Stock

Capillary Electropheresis in Chiral Analysis

Chankvetadze, Bezhan

Cover

1. Edition October 1997
XVI, 556 Pages, Hardcover
Wiley & Sons Ltd

Short Description

Electrophoretic techniques are used to separate large charged molecules such as proteins and sugars. Capillary electrophoresis (CE) allows separation on a very small scale: chiral analysis is the separation of different molecules that are mirror images of one another. As regulations around the world demand increasing levels of purity of chiral molecules, CE is becoming a very important technique for safeguarding the public's health. This book is both an in-depth introduction and a comprehensive review of current technology regarding the applications of CE in chiral analysis.

ISBN: 978-0-471-97415-4
John Wiley & Sons

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Capillary Electrophoresis in Chiral Analysis Bezhan Chankvetadze Tbilisi State University, Republic of Georgia The application of capillary electrophoresis (CE) to the field of chiral analysis has exploded recently. The advantages of capillary electrophoresis - extremely high peak efficiency, excellent compatibility with biological samples, short analysis time, simplicity, versatility and low cost - are perfect for the accurate measurement of optical purity, increasingly important in the regulation-ruled pharmaceutical industry. Although there have been a number of books on capillary electrophoresis and chiral analysis separately, as yet there has been no dedicated monograph on the application of capillary electrophoresis to chiral analysis. This book bridges the gap. Capillary Electrophoresis in Chiral Analysis charts the evolution of chiral capillary electrophoresis and describes new types of chiral selectors and mechanistic aspects of chiral recognition. While on the one hand, it is an excellent introduction to newcomers, on the other, it is of practical use to experienced researchers in the field wishing to solve a particular separation problem. It includes an alphabetical list of chiral compounds resolved using CE with appropriate references, which any one working in the field will find invaluable.

Partial table of contents:

Basics of Capillary Electrophoresis.

Chiral Metal Complexes as Selectors in Capillary Electrophoresis.

Enantioseparation Using Micellar Electrokinetic Chromatography (MEKC).

Crown Ethers as Chiral Selectors in Capillary Electrophoresis.

Macrocyclic Antibiotics as Chiral Selectors in Capillary Electrophoresis.

Enantioseparation in Capillary Electrochromatography (CEC).

Enantiomer Migration Order in Chiral Capillary Electrophoresis.

Appendix.

Index.