Handbook of Nucleoside Synthesis
Organic Reactions
1. Edition August 2001
646 Pages, Softcover
Wiley & Sons Ltd
ISBN:
978-0-471-09383-1
John Wiley & Sons
Handbook of Nucleoside Synthesis includes descriptive information regarding the three principal types of nucleoside forming reactions: the Fusion Reaction, the Metal Salt Procedure, and the Hilbert-Johnson Reaction, as well as other miscellaneous methods.
Foreword.
Preface.
Acknowledgments.
Synthesis of Nucleosides.
Introduction.
Nucleoside Synthesis.
Silyl-Hilbert-Johnson Reaction in the Presence of Friedel-Crafts
Catalysts.
Mechanism of Nucleoside Formation in the Presence of
Friedel-Crafts Catalysts.
Special Preparations.
Miscellaneous Methods.
Alternative Nucleoside-Forming Reactions.
Experimental Conditions.
Experimental Procedures.
Tabular Survey.
References.
Index.
Preface.
Acknowledgments.
Synthesis of Nucleosides.
Introduction.
Nucleoside Synthesis.
Silyl-Hilbert-Johnson Reaction in the Presence of Friedel-Crafts
Catalysts.
Mechanism of Nucleoside Formation in the Presence of
Friedel-Crafts Catalysts.
Special Preparations.
Miscellaneous Methods.
Alternative Nucleoside-Forming Reactions.
Experimental Conditions.
Experimental Procedures.
Tabular Survey.
References.
Index.
"...an insightful and detailed analysis?provides a valuable
resource for the practitioner and a solid foundation for those new
to nucleoside synthesis." (Journal of Medicinal Chemistry,
Vol. 45, No. 4, 2002)
"...contains much more information than one can assemble from a
literature search...allows the reader to compare reaction
conditions and the outcome of the reaction...the value of the book
is considerable increased by the inclusion of experimental details
and protocols based on the experience of the authors...highly
recommended for everybody interested.... It is expected that this
book will become, just like the Vorbruggen reaction itself, a
classic in nucleoside chemistry." (Angewandte Chemie
International Edition, Vol. 41, No. 9, 2002)
"...a comprehensive review of nucleoside synthesis..."
(SciTech Book News, Vol. 26, No. 2, June 2002)
"...clearly written and well-organized...provides excellent
coverage of the contemporary methods used in nucleoside
chemistry..." (ChemBioChem, Vol 4(5), 2003)
resource for the practitioner and a solid foundation for those new
to nucleoside synthesis." (Journal of Medicinal Chemistry,
Vol. 45, No. 4, 2002)
"...contains much more information than one can assemble from a
literature search...allows the reader to compare reaction
conditions and the outcome of the reaction...the value of the book
is considerable increased by the inclusion of experimental details
and protocols based on the experience of the authors...highly
recommended for everybody interested.... It is expected that this
book will become, just like the Vorbruggen reaction itself, a
classic in nucleoside chemistry." (Angewandte Chemie
International Edition, Vol. 41, No. 9, 2002)
"...a comprehensive review of nucleoside synthesis..."
(SciTech Book News, Vol. 26, No. 2, June 2002)
"...clearly written and well-organized...provides excellent
coverage of the contemporary methods used in nucleoside
chemistry..." (ChemBioChem, Vol 4(5), 2003)
HELMUT VORBRUGGEN is Professor of Chemistry at the Free University
in Berlin, Germany.
CARMEN RUH-POHLENZ is Research Scientist at Schering AG in Berlin,
Germany.
in Berlin, Germany.
CARMEN RUH-POHLENZ is Research Scientist at Schering AG in Berlin,
Germany.