Quaternary Stereocenters
Challenges and Solutions for Organic Synthesis
1. Edition August 2005
XXIII, 336 Pages, Hardcover
371 Pictures
61 tables
Handbook/Reference Book
Short Description
By comprehensively covering the quaternary stereocenters found in a range of important and useful molecules in pharmaceutical and medicinal applications, as well as in thousands of natural products, this book provides the know-how chemists need to synthesize important drugs.
Filling the gap in the literature, this book presents everything there is to know about this topic. By comprehensively covering the quaternary stereocenters found in a range of important and useful molecules in pharmaceutical and medicinal applications, as well as in thousands of natural products, the book provides the know-how chemists need to synthesize challenging molecules with numerous applications.
A must for organic chemists in academia, the pharmaceutical industry and medicine.
From the Contents:
Important Natural Products
Important Pharmaceuticals and Intermediates
Aldol Reactions
Michael Reactions and Conjugate Additions
Cycloaddition Reactions
Rearrangement Reactions
Alkylation of Ketones and Imines
Asymmetric Allylic Alkylation
Asymmetric Cross Coupling and Heck Reactions
Phase Transfer Catalysis
Enzymatic Methods
Radical Reactions
Important Pharmaceuticals and Intermediates
Aldol Reactions
Michael Reactions and Conjugate Additions
Cycloaddition Reactions
Rearrangement Reactions
Alkylation of Ketones and Imines
Asymmetric Allylic Alkylation
Asymmetric Cross Coupling and Heck Reactions
Phase Transfer Catalysis
Enzymatic Methods
Radical Reactions
Angewandte Chemie
"..put right an oversight in a most emphatic and informative way...covers a wide range of chemistry...This is a handsome little book and, as well as being destined for the shelves of all institutional libraries, I expect it to become a must for anyone who has any pretensions to the practice of organic synthesis."
Chemistry World
"On the whole, the monograph provides a good and up-to-date overview of the various synthetic techniques available for the diastereo- and enantioselective formation of quaternary carbon centers. It should be of interest to all chemists involved in stereoselective organic synthesis."
Advanced Synthesis & Catalysis
"... should be welcome by anyone involved in the practice or teaching of organic synthesis because it represents a timely overview of a significant topic... I am very much looking forward to having this reference as a guide for all new students in our laboratory."
Journal of Medical Chemistry
"This book is clearly timely and fills an important niche. The chemical practitioner will find it an excellent resource...it also is a useful beginning point for students..."
Journal of the American Chemical Society
"This text should be welcomed by anyone involved in the practice or teaching of organic synthesis..."
Journal of Medicinal Chemistry
Angelika Baro studied chemistry at the Georg-August-Universität Göttingen, Germany, where she received her PhD degree in Clinical Biochemistry in 1987 under the supervision of Professor H. D. Söling. Since 1991 she has been a scientific staff member at the Institute for Organic Chemistry at the University of Stuttgart.