Thiophene and Its Derivatives, Volume 3
The Chemistry of Heterocyclic Compounds (Series Nr. 3)
99. Edition June 2007
552 Pages, Hardcover
Wiley & Sons Ltd
The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects - properties, synthesis, reactions, physiological and industrial significance - of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.
I. General Discussion 1
II. Biological and Pharmacological Activity of Thiophene and Its Derivatives 29
By F. F. Blicke
III. Synthesis and Physical Properties of Thiophene and Its Homologs 47
IV. Molecular Structure and Spectroscopy of Thiophene and Its Derivatives 81
By Frank P. Hochgesang
V. Factors Affecting Substitution Reactions in the Thiophene Nucleus 143
VI. Alkylation, Polymerization, Hydrogenation and Miscellaneous Reac-tions of Thiophene 159
VII. Halothiophenes and Haloalkylthiophenes 173
VIII. The Nitro-and Aminothiophenes 219
IX. Thiophene Compounds Containing Nitrogen in the Side Chain 241
X. Hydroxythiophenes, Thienylalkanols, Alkoxythiophenes, and Thienyl-alkyl Ethers 287
XI. Aldo and Keto Derivatives of Thiophene 307
XII. Carboxy Derivatives of Thiophene 363
XIII. Sulfur Derivatives of Thiophene 417
XIV. Metal and Miscellaneous Metalloid Derivatives of Thiophene 439
XV. Synthesis and Properties of Di- and Polythienyls and Arylthiophenes 459
XVI. Selenophene, Tetrahydroselenophene, Tellurophene, and Tetrahydrotellurophene 479