Wiley-VCH, Weinheim Erythropoietin Cover The first book to cover all aspects from developmental biology to such specific topics as medical ap.. Product #: 978-3-527-30495-0 Regular price: $123.36 $123.36 In Stock

Erythropoietin

Blood, Brain and Beyond

Sytkowski, Arthur J.

Cover

1. Edition January 2004
XIII, 224 Pages, Hardcover
30 Pictures (10 Colored Figures)
3 tables
Monograph

ISBN: 978-3-527-30495-0
Wiley-VCH, Weinheim

Short Description

The first book to cover all aspects from developmental biology to such specific topics as medical applications of recombinant Epo, receptor biology, mechanisms of Epo activity, structure/activity relationship, disease states and non-hematologic actions.

Buy now

Price: 132,00 €

Price incl. VAT, excl. Shipping

Euro prices for Wiley-VCH and Ernst & Sohn titles are only valid for Germany. In EU countries, local VAT applies. Postage will be charged.

- Out of print -

Further versions

pdf

The use of Epo in medical practice is increasing constantly. It has revolutionized how we think of blood transfusion in medicine and surgery. Moreover, it has become widely known to scientists, physicians, biotech and pharmaceutical executives and the general public. Additionally, the past ten years have seen important advances in our knowledge and understanding of its action both within and outside of the hematopoietic system.

Until now, there has been no single source that contains up-to-date information on Epo addressing the array of subjects that this book presents.

The book covers all aspects from developmental biology to specific topics such as medical applications of recombinant Epo, receptor biology, mechanisms of Epo activity, structure/activity relationship, disease states and important actions on non-hematopoietic organs and tissues, including the central nervous system, heart, gastrointestinal tract, reproductive organs and endothelium.

1. Introduction and History
2. Developmental Biology of Erythropoiesis and Erythropoietin Production
3. Regulation of the Erythropoietin Gene: A Paradigm for Hypoxia Dependent Genes
4. Physiology and Metabolism of Erythropoietin
5. Biochemistry and Protein Structure
6. Receptor Biology and Signal Transduction
7. Clinical Disorders of Erythropoietin and its Receptor
8. Recombinant Erythropoietin and the Treatment of Anemia
9. Function of Erythropoietin Outside of Hematopoiesis
10. Erythropoietin and Sport
11. The Future of Erythropoietin
"... in einem einzigen Buch den weiten Informationsbereich über die Wirkweise und Anwendung von Erythropoietin komprimiert."
Arzneimittel-Forschung
Dr. Arthur Sytkowski received his Doctor of Medicine from the Medical College of Wisconsin and worked as a Research Associate in the Laboratory of Biochemical Genetics, National Heart, Lung and Blood Institute (NHLBI), NIH, Bethesda. In 1977, he joined Harvard Medical School, and established his research on the structure and function of human erythropoietin.
Current research interests include therapeutic protein engineering, the control of blood cell differentiation, mechanisms of neoplasia, biological effects of microgravity, ligand/receptor biochemistry, growth factor signal transduction, gene regulation and cancer chemoprevention.

A. J. Sytkowski, Beth Israel Deaconess Medical Center, Boston, USA