Modern Amination Methods

1. Edition July 2000
XVIII, 267 Pages, Hardcover
184 Pictures
33 tables
Handbook/Reference Book
Short Description
This first book to provide an overview of the latest and most effective amination methods compiles all of the knowledge previously scattered in numerous journals in one concise volume. Written by an internationally renowned team of experts, including E. M. Carreira (ETH Zürich), J. F. Hartwig (Yale Univ.), K. A. Jorgensen (Aarhus Univ.), this handbook guarantees thorough and competent coverage of a topical subject.
Organic compounds containing amino groups are at the center of modern organic chemistry, and are widely used in the pharmaceutical industry, crop protection, natural product chemistry, and in advanced materials. Modern methods for the introduction of the amino group are therefore of major importance to synthetic chemists and product developers.
Over the last decade, many methods have been developed to generate new C-N bonds. At the same time, the pharmaceutical and chemical industry was rapidly moving away from the development of racemic compounds to the direct synthesis of enantiomerically pure materials. The articles of this book, written by internationally recognized experts, thus focus on asymmetric synthesis.
The most recent catalytic amination methods have particularly revolutionized the chemistry of amino compounds - and you find them all in this first comprehensive overview.
Stereoselctive electrophilic amination with sulfonyl carbamates and azodicarboxylates
Transition Metal-Catalysed Amination to form Aromatic Carbon-Nitrogen Bonds
Glycosylamines as the Stereodifferentiating Tools in Enantioselective Synthesis of Amino Acids and N-Heterocycles
Allylic Amination Reactions
Chiral nitrido-MN complexes and their use in asymmetric synthesis of aziridines
Asymmetric electrophilic amination
Organic Process Research and Development Jnl.