Common Contact Allergens
A Practical Guide to Detecting Contact Dermatitis
1. Edition January 2020
352 Pages, Hardcover
Practical Approach Book
Further versions
How to diagnose allergic contact dermatitis, perform and interpret patch tests, and select the best treatment options
Written for a broad range of dermatologic professionals, Common Contact Allergens is a straightforward and useful guide that bridges the gap between detailed reference texts and basic handbooks on contact allergy, making it an ideal addition to general dermatology practices for practical use in the office.
The first section of the book leads practitioners through the steps necessary to effectively and accurately perform patch testing. This covers basic immunological knowledge, various ways in which contact allergy can present, patch test techniques, and how to diagnose allergic contact dermatitis. Giving attention to all standard allergens, the second section offers an overview of the current literature on each, with detailed analysis on determining the clinical relevance of a positive patch test reaction. This convenient companion:
* Offers universally applicable guidance on when and how to perform patch testing, as well as how to interpret test reactions and arrive at accurate diagnoses
* Characterizes allergens from the Standard 'Baseline' Series, the International Series, and the T.R.U.E. Test Series
* Profiles allergens such as metals, fragrances, medicaments, rubber chemicals, plant chemicals, hair and clothing dyes, excipients, and resins
* Contains case reports, clinical images, patch test tips, and more
* Features color-coded exposure templates for easy consultation
* Provides key pointers on how to take patient histories and handle challenging cases
* Introduces new concepts such as 'microhistory' and 'microexamination'
* Allows access to online supplementary material featuring CAS numbers, toxicology, immunology, prevalence rates, chemical structures, additional case reports, and more
Common Contact Allergens is a valuable reference tool for trainee and practicing general dermatologists, dermatology nurses, occupational health physicians, allergists, and other medical professionals with an interest in dermatology.
Preface xi
About the Companion Website xiii
Section 1: Methodology 1
1 Immunology of Allergic Contact Dermatitis 3
2 Patch Test Technique 5
3 The Detective's Guide to Contact Dermatitis 15
4 History, Microhistory, and Sources of Contact Allergen Exposure 23
5 Microexamination 55
6 Setting up a Patch Test Practice 89
7 The Role of Providers of Patch Test Products 93
Section 2: Non-Allergic Dermatoses 99
8 Elimination or Inclusion of Non-Allergic Skin Diseases 101
9 Irritant Contact Dermatitis 123
Section 3: Common Contact Allergens 127
Metals 129
10 Nickel 129
11 Cobalt 145
12 Chromate 151
13 Gold 161
Fragrances 167
14 Fragrances Incorporating Fragrance Mix 1, Fragrance Mix 2, Hydroxyisoheyl 3-cyclohexene Carboxaldehyde, Limonene, and Linalool 167
Preservatives 181
15 Formaldehyde 181
16 Quaternium-15 187
17 Diazolidinyl Urea and Imidazolidinyl Urea 191
18 2-Bromo-2-nitropropane-1,3-diol 197
19 Methylchloroisothiazolinone/Methylisothiazolinone 201
20 Methylisothiazolinone 205
21 Parabens 211
Dyes 217
22 para-Phenylenediamine 217
23 Disperse Blue 106 227
Rubber 233
24 Rubber: Mercaptobenzothiazole, Mercapto Mix, Thiurams, Carbamates, Thioureas, N Isopropyl-N'-Phenyl-pphenylenediamine 233
Resins 245
25 Colophonium 245
26 Epoxy Resin 255
27 Tosylamide Formaldehyde Resin 263
28 para-Tertiary-Butylphenol Formaldehyde Resin 267
Plants 273
29 Sesquiterpene Lactone Mix and Compositae Mix 273
30 Primin 281
Medicaments 287
31 Neomycin 287
32 Clioquinol 293
33 Benzocaine 297
34 Tixocortol-21-pivalate Budesonide, and Hydrocortisone 17-butyrate 303
Others 311
35 Lanolin 311
36 Cetearyl Alcohol 317
Index 321
E-Supplements
10 Nickel
11 Cobalt
12 Chromate
14 Fragrances
15 Formaldehyde
16 Quaternium 15
17 Diazolidinyl Urea and Imidazolidinyl Urea
19 Methylchloroisothiazolinone/Methylsiothiazolinone
20 Methylisothiazolinone
21 Parabens
22 para-Phenylenediamine
24 Rubber
25 Colophonium
26 Epoxy Resin
28 4-tert-Butylphenol Formaldehyde Resin
29 Sesquiterpene Lactone Mix and Compositae Mix
30 Primin
31 Neomycin
32 Clioquinol
33 Benzocaine
34 Corticosteroids: Tixocortol-21-pivalate, Budesonide, and Hydrocortisone 17-butyrate
35 Lanolin
PAILIN PUANGPET, Consultant Dermatologist, Occupational and Contact Dermatitis Clinic, Institute of Dermatology, Bangkok, Thailand.
KORBKARN PONGPAIROJ, Consultant Dermatologist, Division of Dermatology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
SUPITCHAYA THAIWAT, Consultant Dermatologist, Contact Dermatitis Clinic, Division of Dermatology, Department of Internal Medicine, Phramongkutklao Hospital, Bangkok, Thailand.
LEE SHAN XIAN, Consultant Dermatologist, Department of Dermatology, Changi General Hospital, Singapore.
