Surgical Management of Vitiligo
1. Edition October 2006
304 Pages, Hardcover
Wiley & Sons Ltd
Although vitiligo has traditionally been very difficult to treat, a
new breakthrough surgical treatment is expanding options for
practitioners and patients.
Standard treatments depend on the severity of the condition and
the patient's feelings of disfigurement. Cover-up cosmetics work
well for some people. Other more sophisticated forms of treatment
include gradually developing color back in the depigmented areas
(repigmentation) by PUVA or other ultraviolet light treatments, but
this is extremely slow and intensive, often requiring several
hundred treatments.
This new form of treatment, which involves surgically
transplanting melanocytes into the white areas, is most successful
in patients with stable vitiligo over less than 30% of their body
surface area. It complements medical therapies in achieving
complete and sustained repigmentation and is rapidly gaining
popularity in all major centers.
This is the first book available which describes this major
advance in detail.
* * Explains the new treatment of surgically transplanting
melanocytes into the affected areas of the skin to provide
dermatologists and surgeons with the latest state-of-the-art
information
* * Written by the international leaders who pioneered this
treatment
* * Presents all the latest information on the topic, eliminating
the need to search through multiple sources for specific data
1 Pathogenesis of vitiligo.
2 Understanding the mechanism of repigmentation in vitiligo.
3 Classification of vitiligo.
4 Medical treatment of vitiligo.
Section 2 Overview of surgical management.
5 History and chronology of development of surgical therapies
for vitiligo.
6 The concept of stability of vitiligo.
7 Patient selection and preoperative information in surgical
therapies for vitiligo.
8 Classification of surgical therapies for vitiligo.
9 Surgical management of vitiligo and other leukodermas:
evidence-based.
practice guidelines.
10 Evaluation of outcome in surgical therapies for vitiligo.
Section 3 Tissue grafting.
11 Minigrafting for vitiligo.
12 Suction blister epidermal grafting.
13 Thin split-thickness skin grafts for vitiligo.
14 Treatment of leukoderma by transplantation of ultra-thin
epidermal sheets.
15 Transplantation of hair follicles for vitiligo.
16 Mesh grafts for vitiligo.
17 Flip-top pigment transplantation.
18 Ultrasonic abrasion and seed grafts for vitiligo.
19 Complications and limitations of melanocyte
transplantation.
Section 4 Cellular grafting.
20 Treatment of leukoderma by transplantation of basal cell
layer suspension.
21 Setting up a tissue culture laboratory.
22 Treatment of leukoderma by transplantation of cultured
autologous.
melanocytes.
23 Transplantation of in vitro cultured epithelial grafts for
vitiligo and.
piebaldism.
24 Simplifying the delivery of cultured melanocytes and
keratinocytes for.
grafting patients with vitiligo.
25 Safety concerns in transplantation of in vitro cultured
cellular grafts.
Section 5 Special issues.
26 Post-surgery patient information.
27 Surgical management of lip vitiligo.
28 Surgical management of vitiligo of eyelids and genitals:
special issues.
29 Surgical management of acral vitiligo.
30 Surgical management of leukotrichia.
31 Surgical treatments of leukodermas other than vitiligo
vulgaris.
Section 6 Miscellaneous.
32 Micropigmentation.
33 Laser for repigmenting vitiligo.
34 Application of lasers in transplantation procedures for
vitiligo.
35 Combining medical and surgical therapies.
36 Surgical depigmentation of vitiligo: bleaching cream, laser
and cryosurgery.
37 Future directions in surgical management of vitiligo.
38 Informed consent.
possible new ways to transplant autologous melanocytes from areas
of pigmented skin to areas of leukoderma in patients with vitiligo
and several other forms of leukoderma...
... it should be in the library of all those involved in this
type therapy. It will expand the surgical armamentarium of those
with interests in the surgical management of vitiligo."
- James J. Nordlund, MD Dayton, Ohio(J AM ACAD DERMATOL) VOLUME
57, NUMBER 6
"...this is a wonderfully comprehensive textbook and is a
bargain as well. Because most dermatologic surgeons see pigmentary
disorders...this book would make a nice addition to
libraries."
Dermatological Surgery
"A welcome surprise...a comprehensive monograph on all
the current and new ways to transplant...should be in the
library of all those involved in this therapy."
Journal of the American Medical Association
Department of Dermatology and Venereology
All India Institute of Medical Sciences
New Delhi, India
Mats J. Olsson, PhD
Department of Medical Sciences
Section of Dermatology and Venereology
University Hospital
Uppsala, Sweden
Amrinder J. Kanwar, MD
Department of Dermatology, Venereology and Leprology
Postgraduate Institute of Medical Education and Research
Chandigarh, India
Jean-Paul Ortonne, MD
Department of Dermatology
Nice University Hospital
Nice, France
