Destruction of Hazardous Chemicals in the Laboratory
4. Edition January 2023
880 Pages, Hardcover
Practical Approach Book
Further versions
Destruction of Hazardous Chemicals in the Laboratory
Single volume reference providing procedural information for the destruction of a wide variety of hazardous chemicals
Destruction of Hazardous Chemicals in the Laboratory is a practical reference that describes procedures for the destruction of a comprehensive list of hazardous chemicals and provides general methods for the destruction of hazardous chemicals in the laboratory without the need for exotic reagents and equipment.
Unlike most other sources on this subject, detailed reaction parameters are provided to readers. These details will help the reader decide if a procedure will be appropriate. To further aid in reader comprehension, numerous tables throughout the book allow for ready comparison of procedures.
Destruction of Hazardous Chemicals in the Laboratory also describes the critical aspects of various protocols (e.g., UV lamp type and rate of ozone flow).
The updated fourth edition Includes an updated survey of the literature from 2012-2021 and features data mined from 1,500 papers. It also describes recent examples of methods that are generally applicable to organic compounds and greatly expands the section on methods for the destruction of pharmaceuticals in the laboratory.
In this book, readers can expect to find detailed information on:
* Specific methods for the destruction of hazardous chemicals in the laboratory, such as aflatoxins, butyllithium, complex metal hydrides, ethidium bromide, MPTP, nitrosamines, and polycyclic aromatic hydrocarbons
* Methods for the destruction of pharmaceuticals in the laboratory, such as those using ozone, persulfate, and potassium permanganate as well as photolytic degradation procedures
* Procedures for drying organic solvents
* A discussion of the issues concerning nitrosamine formation during the destruction process, particularly when sodium hypochlorite is used
* A variety of indexes, including a general index, cross index of pharmaceuticals and destruction procedures, cross index of dyes and destruction procedures, and cross index of names for dyes and biological stains
Destruction of Hazardous Chemicals in the Laboratory is of immense value to researchers in the laboratory by enabling them to quickly and efficiently get rid of residual amounts of hazardous chemicals when a series of experiments has ended. The procedures in the text can also be incorporated into laboratory protocols.
Acknowledgments XXX
Introduction XXX
SPECIFIC METHODS FOR THE DESTRUCTION OF HAZARDOUS CHEMICALS IN THE LABORATORY XXX
ACETONITRILE XXX
ACID HALIDES AND ANHYDRIDES XXX
AFLATOXINS XXX
ALKALI AND ALKALINE EARTH METALS XXX
ALKALI METAL ALKOXIDES XXX
ANATOXIN-A XXX
AROMATIC AMINES XXX
ARSENIC XXX
AZIDES XXX
AZO AND AZOXY COMPOUNDS AND TETRAZENES XXX
BORON TRIFLUORIDE AND INORGANIC FLUORIDES XXX
BOTULINUM TOXINS XXX
BREVETOXINS XXX
BUTYLLITHIUM XXX
CALCIUM CARBIDE XXX
CARBAMIC ACID ESTERS XXX
CARBOFURAN XXX
CHLOROMETHYLSILANES AND SILICON TETRACHLORIDE XXX
N-CHLOROSUCCINIMIDE AND CHLORAMINE-T XXX
CHLOROSULFONIC ACID XXX
CHROMIUM(VI) XXX
CITRININ XXX
COMPLEX METAL HYDRIDES XXX
CYANIDES AND CYANOGEN BROMIDE XXX
CYLINDROSPERMOPSIN XXX
DIISOPROPYL FLUOROPHOSPHATE XXX
DIMETHYL SULFATE AND RELATED COMPOUNDS XXX
DYES AND BIOLOGICAL STAINS XXX
INTRODUCTION XXX
Decontamination Procedures XXX
Destruction Procedures XXX
Analytical Procedures, Mutagenicity Assays, and Related Compounds XXX
ETHIDIUM BROMIDE XXX
HALOETHERS XXX
HALOGENATED COMPOUNDS XXX
HALOGENS XXX
HEAVY METALS XXX
HEXAMETHYLPHOSPHORAMIDE XXX
HYDRAZINES XXX
HYPOCHLORITES XXX
MERCURY XXX
2-METHYLAZIRIDINE XXX
1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE(MPTP) XXX
MICROCYSTINS XXX
4-NITROBIPHENYL XXX
3-NITROFLUORANTHENE AND 3-AMINOFLUORANTHENE XXX
NITROGEN TETROXIDE XXX
N-NITROSO COMPOUNDS: NITROSAMIDES XXX
N-NITROSO COMPOUNDS: NITROSAMINES XXX
OCHRATOXIN A XXX
OKADAIC AXID XXX
ORGANIC NITRILES XXX
OSMIUM TETROXIDE XXX
PALYTOXIN XXX
PATULIN XXX
PERACIDS XXX
PEROXIDES AND HYDROPEROXIDES XXX
PHOSGENE XXX
PHOSPHORUS AND PHOSPHORUS PENTOXIDE XXX
PICRIC ACID XXX
POLYCYCLIC AROMATIC HYDROCARBONS XXX
POLYCYCLIC HETEROCYCLIC HYDROCARBONS XXX
beta-PROPIOLACTONE XXX
PROTEASE INHIBITORS XXX
RICIN XXX
SAXITOXIN XXX
SELENIUM COMPOUNDS XXX
SODIUM AMIDE XXX
STERIGMATOCYSTIN XXX
SULFONYL FLUORIDE ENZYME INHIBITORS XXX
SULFUR-CONTAINING COMPOUNDS XXX
T-2 TOXIN AND OTHER TRICOTHECENES XXX
TETRODOTOXIN XXX
TRIACETONE TRIPEROXIDE XXX
URANYL COMPOUNDS XXX
DESTRUCTION OF PHARMACEUTICALS XXX
General Considerations XXX
POTASSIUM PERMANGANATE XXX
NICKEL-ALUMINUM ALLOY REDUCTION XXX
FENTON REACTION XXX
HYDROGEN PEROXIDE XXX
OZONE XXX
FERRATE XXX
PERSULFATE XXX
HYDROGEN PEROXIDE AND HORSERADISH PEROXIDASE XXX
SPECIFIC DEGRADATION PROCEDURES FOR ß-LACTAMS XXX
DECONTAMINATION OF AQUEOUS SOLUTIONS XXX
MISCELLANEOUS CHEMICAL DEGRADATION PROCEDURES XXX
General Considerations For Photolytic Procedures XXX
Photolysis Without Added Reactants (UV Only) XXX
Photolysis With Hydrogen Peroxide (UV/H2O2) XXX
PHOTO-FENTON REACTION XXX
PHOTOLYSIS WITH TITANIUM DIOXIDE (UV/TiO2) XXX
Photolysis with Zinc Oxide (UV/ZnO) XXX
Photolysis with Ozone (UV/O3) XXX
Photolysis with Persulfate (UV/Persulfate) XXX
Photolysis with Chlorine (UV/Cl2) XXX
Miscellaneous Photolytic Procedures (UV/miscellaneous) XXX
XXX
PROCEDURES CLASSIFIED BY METHOD XXX
General Considerations XXX
Potassium Permanganate XXX
Fenton Reaction XXX
Ozone XXX
Persulfate XXX
Miscellaneous Procedures XXX
Photolysis Without Added Reactants (UV only) XXX
Photolysis with hydrogen peroxide (UV/H2O2) XXX
Photo-Fenton Reaction XXX
Photolysis with Titanium Dioxide (UV/TiO2) XXX
Photolysis with Zinc Oxide (UV/ZnO) XXX
Photolysis with Ozone (UV/O3) XXX
Photolysis with Persulfate (UV/Persulfate) XXX
Photolysis with Chlorine (UV/Cl2) XXX
Biologicals XXX
APPENDIX I XXX
APPENDIX II XXX
Index XXX
Eric B. Sansone, Ph.D., was the director of the Environmental Control and Research Program at the NCI-Frederick Cancer Research and Development Center until his retirement.
