John Wiley & Sons Destruction of Hazardous Chemicals in the Laboratory Cover Destruction of Hazardous Chemicals in the Laboratory Single volume reference providing procedural i.. Product #: 978-1-119-84880-6 Regular price: $167.29 $167.29 In Stock

Destruction of Hazardous Chemicals in the Laboratory

Lunn, George / Sansone, Eric B.

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4. Edition January 2023
880 Pages, Hardcover
Practical Approach Book

ISBN: 978-1-119-84880-6
John Wiley & Sons

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Destruction of Hazardous Chemicals in the Laboratory

Single volume reference providing procedural information for the destruction of a wide variety of hazardous chemicals

Destruction of Hazardous Chemicals in the Laboratory is a practical reference that describes procedures for the destruction of a comprehensive list of hazardous chemicals and provides general methods for the destruction of hazardous chemicals in the laboratory without the need for exotic reagents and equipment.

Unlike most other sources on this subject, detailed reaction parameters are provided to readers. These details will help the reader decide if a procedure will be appropriate. To further aid in reader comprehension, numerous tables throughout the book allow for ready comparison of procedures.

Destruction of Hazardous Chemicals in the Laboratory also describes the critical aspects of various protocols (e.g., UV lamp type and rate of ozone flow).

The updated fourth edition Includes an updated survey of the literature from 2012-2021 and features data mined from 1,500 papers. It also describes recent examples of methods that are generally applicable to organic compounds and greatly expands the section on methods for the destruction of pharmaceuticals in the laboratory.

In this book, readers can expect to find detailed information on:
* Specific methods for the destruction of hazardous chemicals in the laboratory, such as aflatoxins, butyllithium, complex metal hydrides, ethidium bromide, MPTP, nitrosamines, and polycyclic aromatic hydrocarbons
* Methods for the destruction of pharmaceuticals in the laboratory, such as those using ozone, persulfate, and potassium permanganate as well as photolytic degradation procedures
* Procedures for drying organic solvents
* A discussion of the issues concerning nitrosamine formation during the destruction process, particularly when sodium hypochlorite is used
* A variety of indexes, including a general index, cross index of pharmaceuticals and destruction procedures, cross index of dyes and destruction procedures, and cross index of names for dyes and biological stains

Destruction of Hazardous Chemicals in the Laboratory is of immense value to researchers in the laboratory by enabling them to quickly and efficiently get rid of residual amounts of hazardous chemicals when a series of experiments has ended. The procedures in the text can also be incorporated into laboratory protocols.

Preface XXX

Acknowledgments XXX


Introduction XXX


SPECIFIC METHODS FOR THE DESTRUCTION OF HAZARDOUS CHEMICALS IN THE LABORATORY XXX

ACETONITRILE XXX

ACID HALIDES AND ANHYDRIDES XXX

AFLATOXINS XXX

ALKALI AND ALKALINE EARTH METALS XXX

ALKALI METAL ALKOXIDES XXX

ANATOXIN-A XXX

AROMATIC AMINES XXX

ARSENIC XXX

AZIDES XXX

AZO AND AZOXY COMPOUNDS AND TETRAZENES XXX

BORON TRIFLUORIDE AND INORGANIC FLUORIDES XXX

BOTULINUM TOXINS XXX

BREVETOXINS XXX

BUTYLLITHIUM XXX

CALCIUM CARBIDE XXX

CARBAMIC ACID ESTERS XXX

CARBOFURAN XXX

CHLOROMETHYLSILANES AND SILICON TETRACHLORIDE XXX

N-CHLOROSUCCINIMIDE AND CHLORAMINE-T XXX

CHLOROSULFONIC ACID XXX

CHROMIUM(VI) XXX

CITRININ XXX

COMPLEX METAL HYDRIDES XXX

CYANIDES AND CYANOGEN BROMIDE XXX

CYLINDROSPERMOPSIN XXX

DIISOPROPYL FLUOROPHOSPHATE XXX

DIMETHYL SULFATE AND RELATED COMPOUNDS XXX


DYES AND BIOLOGICAL STAINS XXX

INTRODUCTION XXX

Decontamination Procedures XXX

Destruction Procedures XXX

Analytical Procedures, Mutagenicity Assays, and Related Compounds XXX

ETHIDIUM BROMIDE XXX

HALOETHERS XXX

HALOGENATED COMPOUNDS XXX

HALOGENS XXX

HEAVY METALS XXX

HEXAMETHYLPHOSPHORAMIDE XXX

HYDRAZINES XXX

HYPOCHLORITES XXX

MERCURY XXX

2-METHYLAZIRIDINE XXX

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE(MPTP) XXX

MICROCYSTINS XXX

4-NITROBIPHENYL XXX

3-NITROFLUORANTHENE AND 3-AMINOFLUORANTHENE XXX

NITROGEN TETROXIDE XXX

N-NITROSO COMPOUNDS: NITROSAMIDES XXX

N-NITROSO COMPOUNDS: NITROSAMINES XXX

OCHRATOXIN A XXX

OKADAIC AXID XXX

ORGANIC NITRILES XXX

OSMIUM TETROXIDE XXX

PALYTOXIN XXX

PATULIN XXX

PERACIDS XXX

PEROXIDES AND HYDROPEROXIDES XXX

PHOSGENE XXX

PHOSPHORUS AND PHOSPHORUS PENTOXIDE XXX

PICRIC ACID XXX

POLYCYCLIC AROMATIC HYDROCARBONS XXX

POLYCYCLIC HETEROCYCLIC HYDROCARBONS XXX

beta-PROPIOLACTONE XXX

PROTEASE INHIBITORS XXX

RICIN XXX

SAXITOXIN XXX

SELENIUM COMPOUNDS XXX

SODIUM AMIDE XXX

STERIGMATOCYSTIN XXX

SULFONYL FLUORIDE ENZYME INHIBITORS XXX

SULFUR-CONTAINING COMPOUNDS XXX

T-2 TOXIN AND OTHER TRICOTHECENES XXX

TETRODOTOXIN XXX

TRIACETONE TRIPEROXIDE XXX

URANYL COMPOUNDS XXX


DESTRUCTION OF PHARMACEUTICALS XXX

General Considerations XXX

POTASSIUM PERMANGANATE XXX

NICKEL-ALUMINUM ALLOY REDUCTION XXX

FENTON REACTION XXX

HYDROGEN PEROXIDE XXX

OZONE XXX

FERRATE XXX

PERSULFATE XXX

HYDROGEN PEROXIDE AND HORSERADISH PEROXIDASE XXX

SPECIFIC DEGRADATION PROCEDURES FOR ß-LACTAMS XXX

DECONTAMINATION OF AQUEOUS SOLUTIONS XXX

MISCELLANEOUS CHEMICAL DEGRADATION PROCEDURES XXX

General Considerations For Photolytic Procedures XXX

Photolysis Without Added Reactants (UV Only) XXX

Photolysis With Hydrogen Peroxide (UV/H2O2) XXX

PHOTO-FENTON REACTION XXX

PHOTOLYSIS WITH TITANIUM DIOXIDE (UV/TiO2) XXX

Photolysis with Zinc Oxide (UV/ZnO) XXX

Photolysis with Ozone (UV/O3) XXX

Photolysis with Persulfate (UV/Persulfate) XXX

Photolysis with Chlorine (UV/Cl2) XXX

Miscellaneous Photolytic Procedures (UV/miscellaneous) XXX

XXX

PROCEDURES CLASSIFIED BY METHOD XXX

General Considerations XXX

Potassium Permanganate XXX

Fenton Reaction XXX

Ozone XXX

Persulfate XXX

Miscellaneous Procedures XXX

Photolysis Without Added Reactants (UV only) XXX

Photolysis with hydrogen peroxide (UV/H2O2) XXX

Photo-Fenton Reaction XXX

Photolysis with Titanium Dioxide (UV/TiO2) XXX

Photolysis with Zinc Oxide (UV/ZnO) XXX

Photolysis with Ozone (UV/O3) XXX

Photolysis with Persulfate (UV/Persulfate) XXX

Photolysis with Chlorine (UV/Cl2) XXX

Biologicals XXX


APPENDIX I XXX


APPENDIX II XXX


Index XXX
George Lunn, Ph.D., has been working as a review chemist for the FDA's Office of Pharmaceutical Quality since 1996. Previously he was a senior research scientist in the Environmental Control and Research Program at the NCI-Frederick Cancer Research and Development Center.

Eric B. Sansone, Ph.D., was the director of the Environmental Control and Research Program at the NCI-Frederick Cancer Research and Development Center until his retirement.